Developmental disorder in children is a heartbreaking parents. Several studies have found that the condition of pregnancy plays an important role for the development of the baby. But in fact, a recent study found that a genetic mutation in the father who did most trigger the disorder in children.
Researchers have found that human genetic mutations inherited most of his father's side. Risk gene mutation may increase with age age of the father.
"Most child development disorders originate from mutations in a gene on the father," said David Reich, professor of genetics at Harvard Medical School, as reported by Counsel and Heal, Monday (08/27/2012).
Reich prof conclusion was based research which found that the ratio of the rate of mutation in the father is 3.3 times compared to the mother. In addition, the rate of gene mutation dad will increase 2-fold at the age of 20-58 years, but not the mother.
The research published the journal Nature Genetics, was conducted on about 85,000 people in Iceland and confirmed that some child developmental disorders such as autism more correlated with the age of the father.
Not only that, this study also calculates the human mutation rate and give you an estimate when did human ancestors began to diverge development of primates. Prof. Reich identified 2058 genes and mutations analyzed mutations in the ancestors of humans and chimps at 3.7 million and 6.6 million years ago.
This study highlights that human genes can undergo drastic changes if the men tend to have children at an older age than previous generations.
Another study published in the journal Nature also shows that older men are more likely to have children with autism or schizophrenia than young men. This is caused by random mutations that occur more as we get older the father, but the mother is not at risk of causing disorder.
The findings concluded that the older the father, the more likely their children with autism or schizophrenia. Cause, the sperm are more susceptible to genetic mutation is produced constantly and often had undergo cell division. And the old man's sperm from his more errors.
0 komentar:
Posting Komentar